The 100 metres hurdles, or 100-meter hurdles, is a track and field event run mainly by women (the male counterpart is the 110 metres hurdles). For the race, ten hurdles of a height of 33 inches (83.8 cm) are placed along a straight course of 100 metres (109.36 yd). The first hurdle is placed after a run-up of 13 metres from the starting line. The next 9 hurdles are set at a distance of 8.5 metres from each other, and the home stretch from the last hurdle to the finish line is 10.5 metres long. The hurdles are set up so that they will fall over if bumped into by the runner, but weighted so this is disadvantageous. Fallen hurdles do not count against runners provided that they do not run into them on purpose. Like the 100 metres sprint, the 100 m hurdles begins with athletes in starting blocks.

The fastest 100 m hurdlers run the distance in a time of around 12.5 seconds. The world record set by Tobi Amusan stands at 12.12 seconds.